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Delayed adenosine therapy is associated with the refractory supraventricular tachycardia in children

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dc.contributor.authorKim, JH-
dc.contributor.authorJung, JY-
dc.contributor.authorLee, SU-
dc.contributor.authorPark, JW-
dc.contributor.authorChoi, JY-
dc.date.accessioned2022-11-11T04:09:30Z-
dc.date.available2022-11-11T04:09:30Z-
dc.date.issued2020-
dc.identifier.issn0735-6757-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/22529-
dc.description.abstractOBJECTIVES: To study the association of time intervals on adenosine therapy with the occurrence of refractory supraventricular tachycardia (SVT) in children. METHODS: We reviewed 334 episodes of presumed SVT requiring adenosine in children (<18years) who visited 4 academic hospital emergency departments (EDs) from July 2013 through June 2017. Refractory SVT was defined as an SVT episode persisting after 2 doses of adenosine. Clinical and electrocardiographic findings, and symptom-to-adenosine (symptom-to-ED plus ED-to-adenosine) time of refractory and responsive SVT episodes were compared. Multivariable logistic regression was performed to identify factors associated with the occurrence of refractory SVT. RESULTS: Of 211 SVT episodes, 42 episodes of refractory SVT (19.9%) were noted (overall sinus conversion rate, 79.6%). The refractory episodes were associated with a higher frequency of known structural heart diseases (9.5% vs. 1.8%; P=0.030) and a longer median ED-to-adenosine time (15.5 vs. 11.0min; P=0.018). The association of the ED-to-adenosine time with refractory SVT remained significant after adjustment (for increment of 1min; aOR, 1.02; 95% CI, 1.007-1.04). CONCLUSIONS: Delayed adenosine therapy is associated with the occurrence of refractory SVT in children, supporting the need for prompt adenosine therapy.-
dc.language.isoen-
dc.subject.MESHAdenosine-
dc.subject.MESHAdministration, Intravenous-
dc.subject.MESHAdolescent-
dc.subject.MESHAnti-Arrhythmia Agents-
dc.subject.MESHChild-
dc.subject.MESHChild, Preschool-
dc.subject.MESHElectrocardiography-
dc.subject.MESHEmergency Service, Hospital-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMale-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTachycardia, Supraventricular-
dc.subject.MESHTime-to-Treatment-
dc.titleDelayed adenosine therapy is associated with the refractory supraventricular tachycardia in children-
dc.typeArticle-
dc.identifier.pmid31787438-
dc.subject.keywordAdenosine-
dc.subject.keywordChild-
dc.subject.keywordEmergency Medicine-
dc.subject.keywordRisk Factors-
dc.subject.keywordSupraventricular-
dc.subject.keywordTachycardia-
dc.contributor.affiliatedAuthorKim, JH-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.ajem.2019.10.018-
dc.citation.titleThe American journal of emergency medicine-
dc.citation.volume38-
dc.citation.number11-
dc.citation.date2020-
dc.citation.startPage2291-
dc.citation.endPage2296-
dc.identifier.bibliographicCitationThe American journal of emergency medicine, 38(11). : 2291-2296, 2020-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1532-8171-
dc.relation.journalidJ007356757-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Emergency Medicine
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