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Effects of socioeconomic status on mortality after Parkinson's disease: A nationwide population-based matched cohort study in Korean populations

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dc.contributor.authorYoon, SY-
dc.contributor.authorShin, J-
dc.contributor.authorChang, JS-
dc.contributor.authorLee, SC-
dc.contributor.authorKim, YW-
dc.date.accessioned2022-11-23T07:32:37Z-
dc.date.available2022-11-23T07:32:37Z-
dc.date.issued2020-
dc.identifier.issn1353-8020-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/22783-
dc.description.abstractINTRODUCTION: To evaluate the mortality rate and impact of SES on mortality in PD using a nationwide cohort in Korea.

METHODS: We selected patients diagnosed with PD (ICD-10 code: G20) and registration code for PD (V124) in the program for rare intractable diseases between 2004 and 2015. After that, atypical parkinsonism was excluded. A matched cohort of individuals without PD were enrolled by randomly matching patients by sex, age, and year of diagnosis to the PD group with a ratio of 1:9. Cox proportional hazard models were used to identify the effects of SES on mortality using Hazard Ratios and 95% confidence intervals.

RESULTS: In total, 26,570 participants were enrolled. The mortality rate was 30.37% in PD cohort and 16.69% in the comparison cohort. According to income level, PD patients in low-middle group revealed significantly decreased HRs of 0.704 (95% CI, 0.533-0.930) compared to those in the lowest group. The medical aid group showed an increased mortality rate (HR = 1.552, 95% CI, 1.191-2.021) compared to the national health insurance group. In the subgroup analyses, medical aid was associated with mortality only in PD with female (HR = 1.740, 95% CI, 1.242-2.438) or aged 60-79 years (HR = 1.434, 95% CI 1.005-2.045). There was no significant difference in mortality rate according to residential area in PD.

CONCLUSIONS: In Korea, individual level low SES including income level and insurance type were significantly associated with increased mortality, whereas regional level SES (residential area) was not related with mortality on PD.
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dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHCohort Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInsurance, Health-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHParkinson Disease-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRural Population-
dc.subject.MESHSex Factors-
dc.subject.MESHSocial Class-
dc.subject.MESHUrban Population-
dc.titleEffects of socioeconomic status on mortality after Parkinson's disease: A nationwide population-based matched cohort study in Korean populations-
dc.typeArticle-
dc.identifier.pmid33129703-
dc.subject.keywordCohort study-
dc.subject.keywordMortality-
dc.subject.keywordParkinson's disease-
dc.subject.keywordSocioeconomic status-
dc.contributor.affiliatedAuthorShin, J-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.parkreldis.2020.10.017-
dc.citation.titleParkinsonism & related disorders-
dc.citation.volume80-
dc.citation.date2020-
dc.citation.startPage206-
dc.citation.endPage211-
dc.identifier.bibliographicCitationParkinsonism & related disorders, 80. : 206-211, 2020-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1873-5126-
dc.relation.journalidJ013538020-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Preventive Medicine & Public Health
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