155 304

Cited 0 times in

Molecular characterization of vancomycin-resistant enterococci from clinical and surveillance specimens.

Authors
Huh, JY; Lee, WG; Jin, HY
Citation
Infection control and hospital epidemiology, 27(10):1076-1080, 2006
Journal Title
Infection control and hospital epidemiology
ISSN
0899-823X1559-6834
Abstract
OBJECTIVE: To compare the molecular characteristics of infection-derived (ID) isolates and intestinal colonization-derived (ICD) isolates of vancomycin-resistant enterococci (VRE) recovered from hospitalized patients.



DESIGN: A 12-month prospective cohort study.



SETTING: A 1,000-bed teaching facility.



METHODS: From January through December 2004, a total of 30 pairs of vanA-containing enterococcal isolates were collected from patients admitted to a teaching hospital in South Korea. Each pair comprised an ID and an ICD VRE isolate from the same patient. All VRE isolates were investigated on the basis of SmaI-restricted pulsed-field gel electrophoresis (PFGE) pattern, Tn1546 type, and presence of the esp gene, including A and C repeat number variation.



RESULTS: Members of 19 pairs (63%) of VRE isolates were genetically indistinguishable from each other. The 11 patients for whom the molecular characteristics of the ID isolates differed from those of the ICD isolates had longer durations of hospitalization and intensive care unit (ICU) stay, compared with the other 19 patients.



CONCLUSIONS: These findings suggest the longer durations of hospitalization and ICU stay may be possible risk factors for colonization with multiple clones of VRE.
MeSH terms
Carrier State/microbiology*Electrophoresis, Gel, Pulsed-FieldEnterococcus/genetics*Enterococcus/isolation & purificationFemaleGram-Positive Bacterial Infections/microbiology*HumansIntensive Care UnitsIntestines/microbiology*KoreaLength of StayMaleMiddle AgedProspective StudiesRisk FactorsVancomycin Resistance*
DOI
10.1086/507961
PMID
17006815
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Laboratory Medicine
AJOU Authors
이, 위교
Full Text Link
Files in This Item:
Full-Text Not Available.txtDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse