Cited 0 times in Scipus Cited Count

Influence of lesion and disease subsets on the diagnostic performance of the quantitative flow ratio in real-world patients

DC Field Value Language
dc.contributor.authorLee, KY-
dc.contributor.authorHwang, BH-
dc.contributor.authorKim, MJ-
dc.contributor.authorChoo, EH-
dc.contributor.authorChoi, IJ-
dc.contributor.authorKim, CJ-
dc.contributor.authorLee, SW-
dc.contributor.authorLee, JM-
dc.contributor.authorKim, MJ-
dc.contributor.authorJeon, DS-
dc.contributor.authorChung, WS-
dc.contributor.authorYoun, HJ-
dc.contributor.authorKim, KJ-
dc.contributor.authorYoon, MH-
dc.contributor.authorChang, K-
dc.date.accessioned2023-01-10T00:38:51Z-
dc.date.available2023-01-10T00:38:51Z-
dc.date.issued2021-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/23827-
dc.description.abstractThe quantitative flow ratio (QFR) is a novel angiography-based computational method assessing functional ischemia caused by coronary stenosis. This study aimed to evaluate the diagnostic performance of quantitative flow ratio (QFR) in patients with angina and acute myocardial infarction (AMI) and to identify the conditions with low diagnostic performance. We assessed the QFR for 1077 vessels under fractional flow ratio (FFR) evaluation in 915 patients with angina and AMI. The diagnostic accuracies of the QFR for identifying an FFR ≤ 0.8 were 95.98% (95% confidence interval [CI] 94.52 to 97.14%) for the angina group and 92.42% (95% CI 86.51 to 96.31%) for the AMI group. The diagnostic accuracy of the QFR in the borderline FFR zones (> 0.75, ≤ 0.85) (91.23% [95% CI 88.25 to 93.66%]) was significantly lower than that in others (difference: 4.32; p = 0.001). The condition accompanying both AMI and the borderline FFR zone showed the lowest QFR diagnostic accuracy in our data (83.93% [95% CI 71.67 to 92.38]). The diagnostic accuracy was reduced for tandem lesions (p = 0.04, not correcting for multiple testing). Our study found that the QFR method yielded a high overall diagnostic performance in real-world patients. However, low diagnostic accuracy has been observed in borderline FFR zones with AMI, and the hybrid FFR approach needs to be considered.-
dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHAngina Pectoris-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Stenosis-
dc.subject.MESHCoronary Vessels-
dc.subject.MESHFemale-
dc.subject.MESHFractional Flow Reserve, Myocardial-
dc.subject.MESHHumans-
dc.subject.MESHIschemia-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Infarction-
dc.subject.MESHSeverity of Illness Index-
dc.titleInfluence of lesion and disease subsets on the diagnostic performance of the quantitative flow ratio in real-world patients-
dc.typeArticle-
dc.identifier.pmid33542310-
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7862355/-
dc.contributor.affiliatedAuthorYoon, MH-
dc.type.localJournal Papers-
dc.identifier.doi10.1038/s41598-021-82235-y-
dc.citation.titleScientific reports-
dc.citation.volume11-
dc.citation.number1-
dc.citation.date2021-
dc.citation.startPage2995-
dc.citation.endPage2995-
dc.identifier.bibliographicCitationScientific reports, 11(1). : 2995-2995, 2021-
dc.identifier.eissn2045-2322-
dc.relation.journalidJ020452322-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
Files in This Item:
33542310.pdfDownload

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse