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Impact of Increased End-Tidal Carbon Dioxide on Continuous Noninvasive Hemoglobin Monitoring during Laparoscopic Gastrectomy: A Randomized Controlled Study

Kim, HY  | Choi, JB  | Han, SU  | Lee, HS | Lee, K | Kim, JE
Journal of personalized medicine, 12(2). : 160-160, 2022
Journal Title
Journal of personalized medicine
The pulse CO-Oximetry allows continuous, noninvasive monitoring of hemoglobin (SpHb). We assessed the impact of increased end-tidal carbon dioxide (EtCO(2)) on the accuracy and trending ability of SpHb in laparoscopic surgery. Participants (n = 64) were randomly allocated to the low carbon dioxide (CO(2)) group (EtCO(2): 30-35 mmHg) or the high CO(2) group (EtCO(2): 40-45 mmHg). The SpHb and laboratory hemoglobin (tHb) were obtained during surgery. The correlation coefficient (r) between SpHb and tHb showed greater tendency in the low CO(2) group (r = 0.68) than in the high CO(2) group (r = 0.43). The bias (precision) was -1.18 (1.09) with a limit of agreement (LOA) of -3.31 to 0.95 in low CO(2) group and -1.02 (1.24) with a LOA of -3.45 to 1.42 in high CO(2) group; they did not differ significantly between the groups (p = 0.246). The low CO(2) group showed a high concordance rate of 95.9% and a moderate correlation between DeltaSpHb and DeltatHb (r = 0.53). However, the high CO(2) group showed a concordance rate of 77.8% and no correlation between DeltaSpHb and DeltatHb (r = 0.11). In conclusion, increased EtCO(2) significantly reduced the trending ability of SpHb during laparoscopic surgery. Caution should be executed when interpreting SpHb values during laparoscopic surgery in patients with hypercapnia.

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Journal Papers > School of Medicine / Graduate School of Medicine > Anesthesiology & Pain Medicine
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
Ajou Authors
김, 지은  |  김, 하연  |  최, 종범  |  한, 상욱
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