Cited 0 times in Scipus Cited Count

Long-Term Clinical Outcomes and Its Predictors Between the 1- and 2-Stent Strategy in Coronary Bifurcation Lesions-A Baseline Clinical and Lesion Characteristic-Matched Analysis

Jang, AY | Kim, M | Oh, PC | Suh, SY | Lee, K | Kang, WC | Choi, KH | Song, YB | Gwon, HC | Kim, HS | Chun, WJ | Hur, SH | Rha, SW | Chae, IH | Jeong, JO | Heo, JH | Yoon, J | Hong, SJ | Park, JS | Hong, MK | Doh, JH | Cha, KS | Kim, DI | Lee, SY | Chang, K | Hwang, BH | Choi, SY  | Jeong, MH | Nam, CW | Koo, BK | Han, SH
Circulation journal, 86(9). : 1365-1375, 2022
Journal Title
Circulation journal
BACKGROUND: Differences in the impact of the 1- or 2-stent strategy in similar coronary bifurcation lesion conditions are not well understood. This study investigated the clinical outcomes and its predictors between 1 or 2 stents in propensity score-matched (PSM) complex bifurcation lesions.Methods and Results: We analyzed the data of patients with bifurcation lesions, obtained from a multicenter registry of 2,648 patients (median follow up, 53 months). The patients were treated by second generation drug-eluting stents (DESs). The primary outcome was target lesion failure (TLF), composite of cardiac death, target vessel myocardial infarction (TVMI), and ischemia-driven target lesion revascularization (TLR). PSM was performed to balance baseline clinical and angiographic discrepancies between 1 and 2 stents. After PSM (N=333 from each group), the 2-stent group had more TLRs (hazard ratio [HR] 3.14, 95% confidence interval [CI] 1.42-6.97, P=0.005) and fewer hard endpoints (composite of cardiac death and TVMI; HR 0.44, 95% CI 0.19-1.01, P=0.054), which resulted in a similar TLF rate (HR 1.40, 95% CI 0.83-2.37, P=0.209) compared to the 1-stent group. Compared with 1-stent, the 2-stent technique was more frequently associated with less TLF in the presence of main vessel (p(interaction)=0.008) and side branch calcification (p(interaction)=0.010). CONCLUSIONS: The 2-stent strategy should be considered to reduce hard clinical endpoints in complex bifurcation lesions, particularly those with calcifications.


Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
Ajou Authors
최, 소연
Full Text Link
Files in This Item:


해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.