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Long-term clinical results and predictors of adverse outcomes after drug-eluting stent implantation for bifurcation lesions in a real-world practice: the COBIS (Coronary Bifurcation Stenting) registry.
DC Field | Value | Language |
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dc.contributor.author | Gwon, HC | - |
dc.contributor.author | Choi, SH | - |
dc.contributor.author | Song, YB | - |
dc.contributor.author | Hahn, JY | - |
dc.contributor.author | Jeong, MH | - |
dc.contributor.author | Seong, IW | - |
dc.contributor.author | Kim, HS | - |
dc.contributor.author | Rha, SW | - |
dc.contributor.author | Yang, JY | - |
dc.contributor.author | Yoon, JH | - |
dc.contributor.author | Tahk, SJ | - |
dc.contributor.author | Seung, KB | - |
dc.contributor.author | Jang, Y | - |
dc.contributor.author | Park, SJ | - |
dc.date.accessioned | 2011-05-13T06:19:24Z | - |
dc.date.available | 2011-05-13T06:19:24Z | - |
dc.date.issued | 2010 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/2591 | - |
dc.description.abstract | BACKGROUND: Limited data exists regarding long-term clinical results and predictors of adverse outcomes after drug-eluting stents (DES) implantation for coronary bifurcation lesions in a real-world practice.
METHODS AND RESULTS: A total of 1,691 non-left main bifurcation lesions with side branches ≥2.0mm in 1,668 patients undergoing DES implantation between January 2004 and June 2006 from 16 centers in Korea were evaluated. True bifurcation was found in 69.2% of lesions and 82.7% of lesions were treated with 1-stent technique. During follow-up (median 22 months), cardiac death occurred in 0.9%, myocardial infarction (MI) in 1.2%, target lesion revascularization (TLR) in 4.7% and stent thrombosis in 0.7% of patients. There was no significant difference in major adverse cardiac events (MACE: composite of cardiac death, MI and TLR) between the 1-stent and the 2-stent groups (6.1% vs 7.5%, P=0.36). Stent length in the main vessel (hazard ratio (HR) 1.02, 95% confidence interval (CI) 1.001-1.03, P=0.03), paclitaxel-eluting stent (HR 1.98, 95%CI 1.34-2.92, P=0.001) and kissing ballooning (HR 2.01, 95%CI 1.29-3.13, P=0.002) were independent predictors of MACE. Kissing ballooning increased the risk of MACE especially in the 1-stent group, but not in the 2-stent group. CONCLUSIONS: In this large real-world registry, overall outcomes after DES implantation in bifurcation lesions were favorable and similar between the 1-stent and 2-stent groups. | - |
dc.language.iso | en | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary | - |
dc.subject.MESH | Chi-Square Distribution | - |
dc.subject.MESH | Coronary Angiography | - |
dc.subject.MESH | Coronary Stenosis | - |
dc.subject.MESH | Drug-Eluting Stents | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Infarction | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Prosthesis Design | - |
dc.subject.MESH | Registries | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Thrombosis | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Long-term clinical results and predictors of adverse outcomes after drug-eluting stent implantation for bifurcation lesions in a real-world practice: the COBIS (Coronary Bifurcation Stenting) registry. | - |
dc.type | Article | - |
dc.identifier.pmid | 20890049 | - |
dc.identifier.url | http://joi.jlc.jst.go.jp/JST.JSTAGE/circj/CJ-10-0352?from=PubMed | - |
dc.contributor.affiliatedAuthor | 탁, 승제 | - |
dc.type.local | Journal Papers | - |
dc.citation.title | Circulation journal | - |
dc.citation.volume | 74 | - |
dc.citation.number | 11 | - |
dc.citation.date | 2010 | - |
dc.citation.startPage | 2322 | - |
dc.citation.endPage | 2328 | - |
dc.identifier.bibliographicCitation | Circulation journal, 74(11). : 2322-2328, 2010 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.relation.journalid | J013469843 | - |
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