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Leptin and ghrelin in Korean systemic lupus erythematosus.

Authors
Kim, HA; Choi, GS; Jeon, JY; Yoon, JM; Sung, JM; Suh, CH
Citation
Lupus, 19(2):170-174, 2010
Journal Title
Lupus
ISSN
0961-20331477-0962
Abstract
Elevated serum leptin levels have been described in patients with systemic lupus erythematosus (SLE), however these studies have provided no information regarding the ghrelin levels. We investigated the clinical significance of serum leptin and ghrelin levels in SLE. The leptin levels of SLE patients were higher than those of normal healthy controls, while the ghrelin levels of the SLE were lower. In addition, the ghrelin levels were significantly lower in SLE patients with arthritis and hematologic disorder. Taken together, these findings suggest that leptin and ghrelin play a role in clinical manifestations observed in SLE.
MeSH terms
AdultArthritis/blood/complicationsAsian Continental Ancestry GroupCase-Control StudiesFemaleGhrelin/*bloodHematologic Diseases/blood/complicationsHumansKoreaLeptin/*bloodLupus Erythematosus, Systemic/*bloodMaleProspective StudiesYoung Adult
DOI
10.1177/0961203309350321
PMID
19965946
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Journal Papers > School of Medicine / Graduate School of Medicine > Rheumatology
AJOU Authors
김, 현아최, 길순서, 창희
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