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Stepwise evolution from a focal pure pulmonary ground-glass opacity nodule into an invasive lung adenocarcinoma: an observation for more than 10 years.

Authors
Min, JH | Lee, HY | Lee, KS | Han, J | Park, K | Ahn, MJ | Lee, SJ
Citation
Lung cancer (Amsterdam, Netherlands), 69(1). : 123-126, 2010
Journal Title
Lung cancer (Amsterdam, Netherlands)
ISSN
0169-50021872-8332
Abstract
The natural chronologic evolution of a lung cancer manifesting as a pure ground-glass opacity (GGO) nodule on CT scans still remains to be elucidated. Therefore, it is sometimes difficult to determine proper follow-up examinations, particularly in case of GGO nodule growing slowly on serial CT scans. In the current case, we demonstrate serial morphologic (CT) and metabolic ((18)F-FDG PET) imaging findings in a case of adenocarcinoma, where stepwise progression from a focal pure GGO nodule (presumed atypical adenomatous hyperplasia [AAH] or bronchioloalveolar carcinoma [BAC]) eventually to an invasive adenocarcinoma was clearly depicted for more than 10-year follow-up period. This case seems to be useful for the prediction of tumor growth pattern and aggressiveness of malignant pure GGO nodules. In addition, the evolving process of this case may suggest a guideline for planning an appropriate follow-up examination and management in such cases.
MeSH

DOI
10.1016/j.lungcan.2010.04.022
PMID
20478641
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Nuclear Medicine & Molecular Imaging
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