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Ketonuria after fasting may be related to the metabolic superiority.

Authors
Joo, NS; Lee, DJ; Kim, KM; Kim, BT; Kim, CW; Kim, KN; Kim, SM
Citation
Journal of Korean medical science, 25(12):1771-1776, 2010
Journal Title
Journal of Korean medical science
ISSN
1011-89341598-6357
Abstract
Obese individuals are less able to oxidize fat than non-obese individuals. Caloric reduction or fasting can detect ketonuria. We investigated the differences of metabolic parameters in the presence of ketonuria after a minimum 8 hr fast in a cross-sectional analysis of 16,523 Koreans (6,512 women and 10,011 men). The relationship between the presence of ketonuria of all subjects and prevalence of obesity, central obesity, metabolic syndrome, and obesity-related metabolic parameters were assessed. The ketonuria group had lower prevalence of obesity, central obesity, and metabolic syndrome than the non-ketonuria group. In addition, all metabolic parameters (including body weight, waist circumference, blood glucose, high-density lipoprotein, triglyceride, blood pressure, and insulin) were favorable in the ketonuria group than in the non-ketonuria group, even after adjustment for age, tobacco use, and alcohol consumption. The odds ratios of having obesity (odds ratio [OR]=1.427 in women, OR=1.582 in men, P<0.05), central obesity (OR=1.675 in women, OR=1.889 in men, P<0.05), and metabolic syndrome (OR=3.505 in women, OR=1.356 in men, P<0.05) were increased in the non-ketonuria group compared to the ketonuria group. The presence of ketonuria after at least an 8 hr fast may be indicative of metabolic superiority.
MeSH terms
Blood Glucose/analysisBlood PressureBody WeightCross-Sectional Studies*FastingFemaleHumansInsulin/bloodKetosis/*complications/diagnosisLipoproteins, HDL/bloodMaleMetabolic Syndrome X/*complications/epidemiologyObesity/complications/epidemiologyOdds RatioTime FactorsTriglycerides/bloodWaist Circumference
DOI
10.3346/jkms.2010.25.12.1771
PMID
21165293
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Family Practice & Community Health
AJOU Authors
주, 남석이, 득주김, 광민김, 범택김, 찬원김, 규남
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