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Does long-term lactation protect premenopausal women against hypertension risk? A Korean women's cohort study.

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dc.contributor.authorLee, SY-
dc.contributor.authorKim, MT-
dc.contributor.authorJee, SH-
dc.contributor.authorYang, HP-
dc.date.accessioned2011-06-16T05:50:12Z-
dc.date.available2011-06-16T05:50:12Z-
dc.date.issued2005-
dc.identifier.issn0091-7435-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/2953-
dc.description.abstractBACKGROUND: Little is known about the long-term effect of lactation on maternal cardiovascular health except for a few animal or human experimental studies. The objective of this study was to examine the effects of lactation on the incidence of hypertension in premenopausal women.
METHODS: The data were derived from a cohort study with 6 years follow-up (1995-2000). The cohort was composed of 177,749 Korean premenopausal women, aged 20-59, who had medical evaluations in 1992 and 1994. During the follow-up, blood pressure was measured as part of the 1996, 1998, and 2000 periodic examinations.
RESULTS: In multivariate Cox proportional hazard models, lactation decreased the risk of hypertension (risk ratio, 0.92; 95% confidence interval, 0.90-0.96). Compared with women who with no history of lactation, 1-6 months of lactation decreased the risk of hypertension (RR, 0.90; 95% CI, 0.87-0.93), as did 7-12 months (RR, 0.92; 95% CI, 0.87-0.98) or 13-18 months (RR, 0.93; 95% CI, 0.86-0.99). In particular, the coexistence of obesity and no lactation increased the risk of hypertension (P for interaction = 0.028).
CONCLUSION: This finding suggests that lactation may be a protective factor against hypertension among premenopausal women.
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dc.formattext/plain-
dc.language.isoen-
dc.subject.MESHAdult-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHHypertension-
dc.subject.MESHIncidence-
dc.subject.MESHKorea-
dc.subject.MESHLactation-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHObesity-
dc.subject.MESHPremenopause-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHProspective Studies-
dc.subject.MESHRisk-
dc.titleDoes long-term lactation protect premenopausal women against hypertension risk? A Korean women's cohort study.-
dc.typeArticle-
dc.identifier.pmid15917038-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0091-7435(04)00591-2-
dc.contributor.affiliatedAuthor이, 순영-
dc.type.localJournal Papers-
dc.citation.titlePreventive medicine-
dc.citation.volume41-
dc.citation.number2-
dc.citation.date2005-
dc.citation.startPage433-
dc.citation.endPage438-
dc.identifier.bibliographicCitationPreventive medicine, 41(2). : 433-438, 2005-
dc.identifier.eissn1096-0260-
dc.relation.journalidJ000917435-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Preventive Medicine & Public Health
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