78 281

Cited 0 times in

An experience of the use of Anti-HBc and Anti-HBs for blood donor screening tests at a tertiary hospital blood center in Korea.

Authors
Lim, YA; Yoon, S
Citation
The Korean journal of laboratory medicine, 29(1):59-65, 2009
Journal Title
The Korean journal of laboratory medicine
ISSN
1598-6535
Abstract
BACKGROUND: The aim of this study was to report the first experience of using tests of antibody to hepatitis B core antigen (anti-HBc) and antibody to hepatitis B surface antigen (anti-HBs) for the selection of blood donors in a tertiary hospital blood center in Korea.



METHODS: From January 2005 to December 2007, the data of all eligible donors according to the Korean Blood Regulation Law were analyzed. Anti-HBc testing was performed in all donors, but anti-HBs was tested only in anti-HBc seropositive donors. Anti-HBs negative but anti-HBc positive donors were regarded as ineligible for blood donation. Cost for donor testing was calculated based on Korean health insurance payment schedule from 2005 to 2007.



RESULTS: The seroprevalence of anti-HBc in blood donors was 23.2% (162/699) and increased with increasing age. The proportion of ineligible donors for blood collection was 2.7% (19/699) of total donors and 11.6% (19/162) of anti-HBc seropositive donors. The cost of testing for anti-HBc and anti-HBs was estimated to be about 40% of the total screening cost.



CONCLUSIONS: Although additional donor screening tests for anti-HBc and anti-HBs requires increased cost and relatively small number of donors are additionally excluded by these tests, they are considered to be helpful for the safety of blood products, because our blood center has characteristics with small number of donors and relatively high percentage of donors in the age group of thirties and older.
MeSH terms
AdolescentAdultAge FactorsBlood BanksBlood Donors*Hepatitis B/diagnosisHepatitis B/economicsHepatitis B Antibodies/blood*Hepatitis B Core Antigens/immunology*Hepatitis B Surface Antigens/immunology*HumansKoreaLaboratories, HospitalMiddle AgedSeroepidemiologic StudiesSerologic Tests/economics
DOI
10.3343/kjlm.2009.29.1.59
PMID
19262080
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Laboratory Medicine
AJOU Authors
임, 영애
Full Text Link
Files in This Item:
kjlm-29-59-65.pdfDownload
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse