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A case of hypersensitivity pneumonitis caused by Penicillium species in a home environment.

Authors
Lee, YM; Kim, YK; Kim, SO; Kim, SJ; Park, HS
Citation
Journal of Korean medical science, 20(6):1073-1075, 2005
Journal Title
Journal of Korean medical science
ISSN
1011-89341598-6357
Abstract
We report a case of hypersensitivity pneumonitis in a 30-yr-old female housewife caused by Penicillium species found in her home environment. The patient was diagnosed according to history, chest radiograph, spirometry, high-resolution chest CT, and transbronchial lung biopsy. To identify the causative agent, cultured aeromolds were collected by the open-plate method. From the main fungi cultured, fungal antigens were prepared, and immunoblot analysis with the patient's serum and each fungal antigen was performed. A fungal colonies were isolated from the patient's home. Immunoblotting analysis with the patient's sera demonstrated a IgG-binding fractions to Penicillium species extract, while binding was not noted with control subject. This study indicates that the patient had hypersensitivity pneumonitis on exposure to Penicillium species in her home environment.
MeSH terms
AdultAlveolitis, Extrinsic Allergic/etiology*Alveolitis, Extrinsic Allergic/immunologyAlveolitis, Extrinsic Allergic/microbiology*Antibodies, Fungal/bloodAntigens, FungalEnvironmental MicrobiologyFemaleHousingHumansImmunoglobulin G/bloodKoreaPenicillium/immunology*Penicillium/isolation & purificationPenicillium/pathogenicity*
DOI
10.3346/jkms.2005.20.6.1073
PMID
16361826
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
AJOU Authors
박, 해심
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