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Pathophysiology of functional dyspepsia.

Authors
Lee, KJ  | Kindt, S | Tack, J
Citation
Best practice & research. Clinical gastroenterology, 18(4). : 707-716, 2004
Journal Title
Best practice & research. Clinical gastroenterology
ISSN
1521-69181532-1916
Abstract
Functional dyspepsia is a highly prevalent symptom complex and a heterogeneous disorder. Recent studies showed potential associations between specific pathophysiologic disturbances and dyspeptic symptoms. Delayed gastric emptying reported in about 30% of patients with functional dyspepsia is associated with the symptoms of postprandial fullness, nausea, and vomiting. Impaired gastric accommodation present in 40% of functional dyspepsia patients is found to be associated with early satiety. Hypersensitivity to gastric distension is observed in 37% of functional dyspepsia patients and associated with the symptoms of postprandial pain, belching, and weight loss. Psychosocial factors and altered response to duodenal lipids or acid have also been identified as pathophysiologic mechanisms.
MeSH

DOI
10.1016/j.bpg.2004.04.007
PMID
15324709
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Gastroenterology
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