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Warty squamous cell carcinoma of the vulva in older women: association with human papillomavirus.

Authors
Jang, YH; Kim, YC; Lee, ES
Citation
Yonsei medical journal, 46(1):155-158, 2005
Journal Title
Yonsei medical journal
ISSN
0513-57961976-2437
Abstract
Warty squamous cell carcinoma (WSCC), a rare variant of squamous cell carcinoma occurring in younger women, is primarily associated with human papillomavirus (HPV) infection. Although WSCC appears to exhibit less aggressive behavior than typical well-differentiated squamous cell carcinoma, it bears the risk of regional metastasis. Accordingly, WSCC should be differentiated from other verruciform neoplasms. We describe a rare case of WSCC with a short disease duration occurring in a woman of old age. We found the presence of HPV DNA different from other well-known types of high risk and low risk HPV by DNA chip microarray. These results suggest that various types of HPV can be associated with the pathogenesis of WSCC.
MeSH terms
AgedCarcinoma, Squamous Cell/pathologyCarcinoma, Squamous Cell/virology*FemaleHumansPapillomaviridae*Papillomavirus Infections/complications*Papillomavirus Infections/pathologySkin Neoplasms/pathologySkin Neoplasms/virology*Vulvar Neoplasms/pathologyVulvar Neoplasms/virology*
DOI
10.3349/ymj.2005.46.1.155
PMID
15744819
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dermatology
AJOU Authors
김, 유찬이, 은소
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