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Widespread scleredema accompanied with a monoclonal gammopathy in a patient with advanced ankylosing spondylitis.

Authors
Chang, HK; Kim, YC; Kwon, BS
Citation
Journal of Korean medical science, 19(3):481-483, 2004
Journal Title
Journal of Korean medical science
ISSN
1011-89341598-6357
Abstract
Scleredema is a rare cutaneous mucinosis characterized by chronic diffuse induration of the skin, and it is occasionally associated with a monoclonal gammopathy (MG). Ankylosing spondylitis (AS) is noted to be another, chronic systemic inflammatory disorder of the axial skeleton that may accompany the MG. However, patients with scleredema and AS accompanied with a MG have not been reported in the literature. We here report a 40-yr-old man with scleredema and advanced AS accompanied with a MG of IgA-kappa protein. Widespread, long-standing scleredema has been developed over 10 yrs after the initial manifestation of AS. It is uncertain whether the coexistence of scleredema and AS is more than coincidental.
MeSH terms
AdultCollagen/metabolismHumansImmunoglobulin kappa-Chains/chemistryInflammationLumbar Vertebrae/radiographyMaleMucins/metabolismParaproteinemias/*complications/diagnosisScleredema Adultorum/*complications/diagnosisSkin/pathologySpondylitis, Ankylosing/*complications/diagnosis
DOI
10.3346/jkms.2004.19.3.481
PMID
15201522
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dermatology
AJOU Authors
김, 유찬
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