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Is the prognosis of T1-2N1 colon cancer the same as that of T1-2N0 colon cancer after curative surgery?

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dc.contributor.authorPian, G-
dc.contributor.authorOh, SY-
dc.date.accessioned2023-12-11T05:42:33Z-
dc.date.available2023-12-11T05:42:33Z-
dc.date.issued2023-
dc.identifier.issn0036-5521-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/32007-
dc.description.abstractObjectives: The prognoses of T1-2N0 and T1-2N1 colon cancer after curative surgery remain unclear. This study compared the prognoses of patients with T1-2N0 and T1-2N1 colon cancer after curative surgery. Materials and methods: We retrospectively evaluated 307 consecutive patients with T1-2N0/1 colon cancer who underwent radical surgery at our hospital between January 2010 and December 2016. There were 266 patients with T1-2N0 colon cancer and 41 patients with T1-2N1 colon cancer. After excluding patients with <12 retrieved lymph nodes, 179 patients with T1-2N0 and 32 with T1-2N1 colon cancer were included in the cohort. Results: Overall survival and disease-free survival did not differ between the T1-2N0 and T1-2N1 groups (p = 0.498 and p = 0.681, respectively). Overall survival and disease-free survival were not significantly different between the T1-2N1 + no chemotherapy and T1-2N1 + chemotherapy groups (p = 0.740 and p = 0.765, respectively). Additionally, overall survival and disease-free survival did not differ between the T1-2N0, T1-2N1 + no chemotherapy, and T1-2N1 + chemotherapy groups (p = 0.757 and p = 0.877, respectively), even after excluding patients with <12 retrieved lymph nodes. Conclusions: T1-2N1 has a prognosis as good as that of T1-2N0 colon cancer after curative surgery. Moreover, further research is needed to investigate the efficacy of adjuvant FOLFOX chemotherapy in T1-2N1.-
dc.language.isoen-
dc.subject.MESHColonic Neoplasms-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHHumans-
dc.subject.MESHLymph Nodes-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHPrognosis-
dc.subject.MESHRetrospective Studies-
dc.titleIs the prognosis of T1-2N1 colon cancer the same as that of T1-2N0 colon cancer after curative surgery?-
dc.typeArticle-
dc.identifier.pmid37345584-
dc.subject.keywordchemotherapy-
dc.subject.keywordColon cancer-
dc.subject.keyworddisease-free survival-
dc.subject.keywordsurvival-
dc.subject.keywordT1-2N0-
dc.subject.keywordT1-2N1-
dc.contributor.affiliatedAuthorOh, SY-
dc.type.localJournal Papers-
dc.identifier.doi10.1080/00365521.2023.2222862-
dc.citation.titleScandinavian journal of gastroenterology-
dc.citation.volume58-
dc.citation.number11-
dc.citation.date2023-
dc.citation.startPage1286-
dc.citation.endPage1294-
dc.identifier.bibliographicCitationScandinavian journal of gastroenterology, 58(11). : 1286-1294, 2023-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1502-7708-
dc.relation.journalidJ000365521-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
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