Cited 0 times in Scipus Cited Count

Nomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper

DC Field Value Language
dc.contributor.authorJutel, M-
dc.contributor.authorAgache, I-
dc.contributor.authorZemelka-Wiacek, M-
dc.contributor.authorAkdis, M-
dc.contributor.authorChivato, T-
dc.contributor.authorDel Giacco, S-
dc.contributor.authorGajdanowicz, P-
dc.contributor.authorGracia, IE-
dc.contributor.authorKlimek, L-
dc.contributor.authorLauerma, A-
dc.contributor.authorOllert, M-
dc.contributor.authorO'Mahony, L-
dc.contributor.authorSchwarze, J-
dc.contributor.authorShamji, MH-
dc.contributor.authorSkypala, I-
dc.contributor.authorPalomares, O-
dc.contributor.authorPfaar, O-
dc.contributor.authorTorres, MJ-
dc.contributor.authorBernstein, JA-
dc.contributor.authorCruz, AA-
dc.contributor.authorDurham, SR-
dc.contributor.authorGalli, SJ-
dc.contributor.authorGomez, RM-
dc.contributor.authorGuttman-Yassky, E-
dc.contributor.authorHaahtela, T-
dc.contributor.authorHolgate, ST-
dc.contributor.authorIzuhara, K-
dc.contributor.authorKabashima, K-
dc.contributor.authorLarenas-Linnemann, DE-
dc.contributor.authorvon Mutius, E-
dc.contributor.authorNadeau, KC-
dc.contributor.authorPawankar, R-
dc.contributor.authorPlatts-Mills, TAE-
dc.contributor.authorSicherer, SH-
dc.contributor.authorPark, HS-
dc.contributor.authorVieths, S-
dc.contributor.authorWong, G-
dc.contributor.authorZhang, L-
dc.contributor.authorBilo, MB-
dc.contributor.authorAkdis, CA-
dc.date.accessioned2023-12-11T05:42:35Z-
dc.date.available2023-12-11T05:42:35Z-
dc.date.issued2023-
dc.identifier.issn0105-4538-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/32015-
dc.description.abstractThe exponential growth of precision diagnostic tools, including omic technologies, molecular diagnostics, sophisticated genetic and epigenetic editing, imaging and nano-technologies and patient access to extensive health care, has resulted in vast amounts of unbiased data enabling in-depth disease characterization. New disease endotypes have been identified for various allergic diseases and triggered the gradual transition from a disease description focused on symptoms to identifying biomarkers and intricate pathogenetic and metabolic pathways. Consequently, the current disease taxonomy has to be revised for better categorization. This European Academy of Allergy and Clinical Immunology Position Paper responds to this challenge and provides a modern nomenclature for allergic diseases, which respects the earlier classifications back to the early 20th century. Hypersensitivity reactions originally described by Gell and Coombs have been extended into nine different types comprising antibody- (I-III), cell-mediated (IVa-c), tissue-driven mechanisms (V-VI) and direct response to chemicals (VII). Types I-III are linked to classical and newly described clinical conditions. Type IVa-c are specified and detailed according to the current understanding of T1, T2 and T3 responses. Types V-VI involve epithelial barrier defects and metabolic-induced immune dysregulation, while direct cellular and inflammatory responses to chemicals are covered in type VII. It is notable that several combinations of mixed types may appear in the clinical setting. The clinical relevance of the current approach for allergy practice will be conferred in another article that will follow this year, aiming at showing the relevance in clinical practice where various endotypes can overlap and evolve over the lifetime.-
dc.language.isoen-
dc.subject.MESHBiomarkers-
dc.subject.MESHHumans-
dc.subject.MESHHypersensitivity-
dc.titleNomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper-
dc.typeArticle-
dc.identifier.pmid37814905-
dc.subject.keywordallergic diseases-
dc.subject.keywordEAACI position paper-
dc.subject.keywordhypersensitivity-
dc.subject.keywordnomenclature-
dc.subject.keywordpathophysiology and mechanism-
dc.contributor.affiliatedAuthorPark, HS-
dc.type.localJournal Papers-
dc.identifier.doi10.1111/all.15889-
dc.citation.titleAllergy-
dc.citation.volume78-
dc.citation.number11-
dc.citation.date2023-
dc.citation.startPage2851-
dc.citation.endPage2874-
dc.identifier.bibliographicCitationAllergy, 78(11). : 2851-2874, 2023-
dc.embargo.liftdate9999-12-31-
dc.embargo.terms9999-12-31-
dc.identifier.eissn1398-9995-
dc.relation.journalidJ001054538-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse