Cited 0 times in Scipus Cited Count

Prediction of Intracranial Atherosclerotic Disease-Related Large-Vessel Occlusion Stroke on the Basis of Novel Cerebral Blood Volume Parameters

DC Field Value Language
dc.contributor.authorKoh, S-
dc.contributor.authorPark, SY-
dc.contributor.authorLiebeskind, DS-
dc.contributor.authorChoi, JW-
dc.contributor.authorKim, HK-
dc.contributor.authorChoi, JY-
dc.contributor.authorKim, M-
dc.contributor.authorLee, SJ-
dc.contributor.authorHong, JM-
dc.contributor.authorLee, JS-
dc.date.accessioned2024-02-13T23:27:11Z-
dc.date.available2024-02-13T23:27:11Z-
dc.date.issued2024-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/32214-
dc.description.abstractBACKGROUND: Mechanical thrombectomy is an effective treatment method for large-vessel occlusion stroke (LVOS); however, it has limited efficacy for intracranial atherosclerotic disease (ICAD)-related LVOS. We investigated the use of cerebral blood volume (CBV) maps for identifying ICAD as the underlying cause of LVOS before the initiation of endovascular treatment (EVT). METHODS AND RESULTS: We reviewed clinical and imaging data from patients who presented with LVOS and underwent endovascular treatment between January 2011 and May 2021. The CBV patterns were analyzed to identify an increase in CBV within the hypoperfused area and estimate infarct patterns within the area of decreased CBV. Comparisons were made between the patients with an increase in CBV and those without, and among the estimated infarct patterns: territorial, cortical wedge, basal ganglia-only, subcortical, and normal CBV. Overall, 243 patients were included. CBV increase in the hypoperfused area was observed in 23.5% of patients. A significantly higher proportion of ICAD was observed in those with increased CBV than in those without (56.4% versus 19.8%; P<0.001). Regarding the estimated infarct patterns on the CBV, ICAD was most frequently observed in the normal CBV group (territorial, 14.9%; cortical wedge, 10.0%; basal ganglia-only, 43.8%; subcortical, 35.7%; normal, 61.7%). CBV parameters, including "an increase in CBV," "normal CBV infarct pattern," and "an increase in CBV or normal CBV infarct pattern composite," were independently associated with ICAD. CONCLUSIONS: An increased CBV or normal CBV pattern may be associated with ICAD LVOS on the pretreatment perfusion imaging.-
dc.language.isoen-
dc.subject.MESHBrain Ischemia-
dc.subject.MESHCerebral Blood Volume-
dc.subject.MESHHumans-
dc.subject.MESHInfarction-
dc.subject.MESHIntracranial Arteriosclerosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHStroke-
dc.subject.MESHThrombectomy-
dc.subject.MESHTreatment Outcome-
dc.titlePrediction of Intracranial Atherosclerotic Disease-Related Large-Vessel Occlusion Stroke on the Basis of Novel Cerebral Blood Volume Parameters-
dc.typeArticle-
dc.identifier.pmid38214247-
dc.identifier.urlhttps://www.ahajournals.org/doi/abs/10.1161/JAHA.123.030936?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed-
dc.subject.keywordcerebral blood volume-
dc.subject.keywordemergent large‐vessel occlusion-
dc.subject.keywordintracranial atherosclerotic disease-
dc.subject.keywordmagnetic resonance imaging-
dc.subject.keywordperfusion map-
dc.contributor.affiliatedAuthorKoh, S-
dc.contributor.affiliatedAuthorPark, SY-
dc.contributor.affiliatedAuthorChoi, JW-
dc.contributor.affiliatedAuthorChoi, JY-
dc.contributor.affiliatedAuthorKim, M-
dc.contributor.affiliatedAuthorLee, SJ-
dc.contributor.affiliatedAuthorHong, JM-
dc.contributor.affiliatedAuthorLee, JS-
dc.type.localJournal Papers-
dc.identifier.doi10.1161/JAHA.123.030936-
dc.citation.titleJournal of the American Heart Association-
dc.citation.volume13-
dc.citation.number2-
dc.citation.date2024-
dc.citation.startPagee030936-
dc.citation.endPagee030936-
dc.identifier.bibliographicCitationJournal of the American Heart Association, 13(2). : e030936-e030936, 2024-
dc.identifier.eissn2047-9980-
dc.relation.journalidJ020479980-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Brain Science
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
Journal Papers > School of Medicine / Graduate School of Medicine > Radiology
Files in This Item:
38214247.pdfDownload

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse