4 249

Cited 1 times in

Identification of proximal left anterior descending artery stenosis with thallium-201 defect patterns in patients with angina pectoris.

Authors
Yoon, JK; Lee, KH; Lee, EJ; Kim, YH; Seo, JD; Kim, BT
Citation
The American journal of cardiology, 93(5):549-553, 2004
Journal Title
The American journal of cardiology
ISSN
0002-91491879-1913
Abstract
We determined the accuracy of perfusion defect patterns in predicting the presence of proximal left anterior descending (LAD) artery stenosis in patients with angina pectoris. The development population consisted of 80 patients with single-vessel LAD stenosis and reversible LAD territory defects on thallium-201 tomography. The types of defect patterns associated with angiographic proximal LAD stenosis in this population were categorized as "proximal LAD patterns." The accuracy of these patterns for identifying proximal LAD stenosis was evaluated in a separate validation population of 152 patients with angina pectoris. The development population demonstrated LAD territory defects of type I (most of the LAD territory; n = 12); type II (apex, apicoanterior, and most of the septum; n = 26), type III (septum; n = 19); type IV (anteroseptum; n = 6); type V (apex; n = 10); and type VI patterns (anterolateral wall; n = 7). Patients with type I, II, and IV patterns were highly associated with proximal LAD stenosis (38 of 44 segments), whereas those with type III, V, and VI patterns were mostly related to distal LAD disease (29 of 36 segments). In the validation population, proximal LAD patterns had a sensitivity, specificity, and accuracy of 72%, 95%, and 91%, respectively, for identifying patients with proximal LAD stenosis. Test sensitivity was 86% when patients without LAD territory defects were excluded from analysis. Results were virtually identical in the subgroup of 84 patients with stable angina. Thus, recognition of LAD territory thallium defect patterns is useful for identifying patients with angina who are likely to have proximal LAD stenosis.
MeSH terms
AgedAngina Pectoris/etiology/*radionuclide imagingCohort StudiesCoronary Stenosis/complications/*radionuclide imagingCoronary Vessels/*radionuclide imagingFemaleHumansMaleMiddle AgedPredictive Value of TestsRadiopharmaceuticals/*diagnostic useReproducibility of ResultsThallium Radioisotopes/*diagnostic use*Tomography, Emission-Computed, Single-Photon
DOI
10.1016/j.amjcard.2003.11.016
PMID
14996577
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Nuclear Medicine & Molecular Imaging
AJOU Authors
윤, 준기
Full Text Link
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse