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Protein kinase C inhibitors attenuate protective effect of high glucose against hypoxic injury in H9c2 cardiac cells.
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Moon, CH | - |
| dc.contributor.author | Jung, YS | - |
| dc.contributor.author | Kim, MH | - |
| dc.contributor.author | Park, RM | - |
| dc.contributor.author | Lee, SH | - |
| dc.contributor.author | Baik, EJ | - |
| dc.date.accessioned | 2011-07-27 | - |
| dc.date.available | 2011-07-27 | - |
| dc.date.issued | 2000 | - |
| dc.identifier.issn | 0021-521X | - |
| dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/3610 | - |
| dc.description.abstract | In this study, we demonstrated that PKC inhibitors significantly attenuated the cardioprotective effect produced by high-glucose (22 mM) treatment for 48 h against hypoxic injury in H9c2 cardiac cells. PKC activators mimicked the cardioprotective effect of high glucose. These results suggest a possible role of PKC activation in high-glucose--induced protection. | - |
| dc.language.iso | en | - |
| dc.subject.MESH | Animals | - |
| dc.subject.MESH | Cell Hypoxia | - |
| dc.subject.MESH | Cell Line | - |
| dc.subject.MESH | Drug Antagonism | - |
| dc.subject.MESH | Enzyme Inhibitors | - |
| dc.subject.MESH | Glucose | - |
| dc.subject.MESH | Humans | - |
| dc.subject.MESH | Myocardium | - |
| dc.subject.MESH | Protein Kinase C | - |
| dc.title | Protein kinase C inhibitors attenuate protective effect of high glucose against hypoxic injury in H9c2 cardiac cells. | - |
| dc.type | Article | - |
| dc.identifier.pmid | 11173560 | - |
| dc.identifier.url | http://joi.jlc.jst.go.jp/JST.JSTAGE/jjphysiol/50.645?from=PubMed | - |
| dc.contributor.affiliatedAuthor | 문, 창현 | - |
| dc.contributor.affiliatedAuthor | 정, 이숙 | - |
| dc.contributor.affiliatedAuthor | 이, 수환 | - |
| dc.contributor.affiliatedAuthor | 백, 은주 | - |
| dc.type.local | Journal Papers | - |
| dc.citation.title | The Japanese journal of physiology | - |
| dc.citation.volume | 50 | - |
| dc.citation.number | 6 | - |
| dc.citation.date | 2000 | - |
| dc.citation.startPage | 645 | - |
| dc.citation.endPage | 649 | - |
| dc.identifier.bibliographicCitation | The Japanese journal of physiology, 50(6). : 645-649, 2000 | - |
| dc.identifier.eissn | 1881-1396 | - |
| dc.relation.journalid | J00021521X | - |
- Appears in Collections:
- Journal Papers > School of Medicine / Graduate School of Medicine > Physiology
- Files in This Item:
- 11173560.pdfDownload
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