Two-spotted spider mite (Tetranychus urticae): an important allergen in asthmatic non-farmers symtomatic in summer and fall months.
Jee, YK; Park, HS; Kim, HY; Park, JS; Lee, KY; Kim, KY; Kim, YK; Cho, SH; Min, KU; Kim, YY
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 84(5):543-548, 2000
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology
BACKGROUND: The Tetranychus urticae (two-spotted spider mite, TSM) is a spider mite commonly found on fruit trees, herbaceous plants, and greenhouse flowers.
OBJECTIVE: To evaluate the clinical significance of TSM-derived allergens in non-farmers with asthma living around pear orchards, and to assess the allergenic relationship with house dust mite.
METHODS: Skin prick tests with TSM were performed in 50 asthmatic non-farmers living around pear orchards. The serum TSM-specific IgE was measured in the 16 asthmatics with a positive skin response to TSM. To diagnose TSM-induced asthma, specific bronchial challenges with TSM were performed in the 16 asthmatics. ELISA inhibition tests were performed to assess the allergenic cross-reactivity with house dust mites.
RESULTS: Ten of the 16 asthmatics with positive skin responses to TSM showed a significant bronchoconstriction following inhalation of TSM. Eight of the ten TSM-induced asthmatics had high serum TSM-specific IgE and one showed a positive skin response only to TSM. Their asthmatic symptoms were aggravated seasonally, especially in summer and early fall. On ELISA inhibition tests, partial inhibitions with D. pteronyssinus antigens were noted in sera from five asthmatics with positive skin responses to both TSM and D. pteronyssinus, although no inhibition was noted in serum from an asthmatic with a positive skin response only to TSM.
CONCLUSION: Tetranychus urticae may be an important allergen in asthmatic non-farmers living around pear orchards and TSM extracts contain species-specific allergens as well as commonly shared allergens with house dust mite.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.
Total Visit :2,707,142
Total Download :1,105,022
Today View :194
Ajou University Medical Information & Media Center 164 Worldcup-ro Yeongtong-gu Suwon 16499 Korea / TEL : 031-219-5312 / FAX : 031-219-5314 Copyright (c) Ajou University Medical Information & Media Center All Rights Reserved. AJOU Open Repository는 국립중앙도서관 OAK 보급사업으로 구축되었습니다.