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Physiological regulation of uteroglobin/CCSP expression.

Authors
Chang, A; Ramsay, P; Zhao, B; Park, M; Magdaleno, S; Reardon, MJ; Welty, S; DeMayo, FJ
Citation
Annals of the New York Academy of Sciences, 923181-192, 2000
Journal Title
Annals of the New York Academy of Sciences
ISSN
0077-89231749-6632
Abstract
Uteroglobin/CCSP is expressed specifically in the Clara cells. This allows the gene to be used as a marker to identify the elements regulating the physiologic and cell-specific expression of this gene. The regulation of UG/CCSP by IFN-gamma was shown to be at the level of the proximal promoter by the upregulation of HNF3 beta. This has allowed the determination of the factors responsible for the expression of UG/CCSP.
MeSH terms
AnimalsGene Expression Regulation/*physiologyHumansLung/cytology/*metabolismMiceProteins/*genetics/metabolismRespiratory Mucosa/cytology/*metabolism/secretionUteroglobin/*genetics/metabolism
PMID
11193756
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
AJOU Authors
박, 문성
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