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Osseous metaplasia with functioning bone marrow in hydroxyapatite orbital implants.

DC Field Value Language
dc.contributor.authorLew, H-
dc.contributor.authorShin, DH-
dc.contributor.authorLee, SY-
dc.contributor.authorKim, SJ-
dc.contributor.authorJang, JW-
dc.date.accessioned2011-08-11T05:28:57Z-
dc.date.available2011-08-11T05:28:57Z-
dc.date.issued2000-
dc.identifier.issn0721-832X-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/3732-
dc.description.abstractBACKGROUND: Bone formation within the hydroxyapatite implant has been reported in explanted spheres in humans. Bone-specific differentiation was observed to occur earlier in the pores of spherical hydroxyapatite implants enhanced with osteogenin within the rabbit socket. We observed previously unreported bone marrow formation in a coralline hydroxyapatite implant placed into the rabbit orbit after evisceration.



METHODS: One eye of each of 10 New Zealand white rabbits weighing between 2 and 3 kg was eviscerated and implanted with hydroxyapatite spheres. The explanted hydroxyapatite spheres 20 weeks after surgery were examined under the microscope.



RESULTS: Histopathologic examination of the excised implants showed the presence of trabeculae of mature bone with fatty marrow and hematopoietic elements. Scattered throughout the fatty tissue were bone marrow elements consisting of precursors of the granulocytic and erythroid series and also megakaryocytes.



CONCLUSION: The osseous metaplasia with functioning bone marrow was incidentally observed in the coralline hydroxyapatite implant without the addition of any osteogenesis-inducing agents.
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dc.language.isoen-
dc.subject.MESHAnimals-
dc.subject.MESHBiocompatible Materials-
dc.subject.MESHBone Development-
dc.subject.MESHBone Marrow-
dc.subject.MESHBone Marrow Cells-
dc.subject.MESHBone and Bones-
dc.subject.MESHEye Evisceration-
dc.subject.MESHHydroxyapatites-
dc.subject.MESHMetaplasia-
dc.subject.MESHOrbital Implants-
dc.subject.MESHOsteogenesis-
dc.subject.MESHRabbits-
dc.titleOsseous metaplasia with functioning bone marrow in hydroxyapatite orbital implants.-
dc.typeArticle-
dc.identifier.pmid10853938-
dc.identifier.urlhttps://link.springer.com/content/pdf/10.1007/s004170050366.pdf-
dc.contributor.affiliatedAuthor장, 재우-
dc.type.localJournal Papers-
dc.identifier.doi10.1007/s004170050366-
dc.citation.titleGraefe's archive for clinical and experimental ophthalmology-
dc.citation.volume238-
dc.citation.number4-
dc.citation.date2000-
dc.citation.startPage366-
dc.citation.endPage368-
dc.identifier.bibliographicCitationGraefe's archive for clinical and experimental ophthalmology, 238(4). : 366-368, 2000-
dc.identifier.eissn1435-702X-
dc.relation.journalidJ00721832X-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Ophthalmology
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