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Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.
- Authors
- Jew, SS | Yoon, CH | Lim, DY | Kim, H | Mook-Jung, I | Jung, MW | Choi, H | Jung, YH | Park, HG
- Citation
- Bioorganic & medicinal chemistry letters, 10(2). : 119-121, 2000
- Journal Title
- Bioorganic & medicinal chemistry letters
- ISSN
- 0960-894X1464-3405
- Abstract
- 8 Semi-synthetic derivatives of asiatic acid were prepared and their protective effect against A beta-induced neurotoxicity was evaluated. Among them, asiatic acid (2), and 4, 16 showed 97, 92 and 87% of protective effect, respectively.
- MeSH
- PMID
- 10673093
- Appears in Collections:
- Journal Papers > Research Organization > Brain Disease Research Center
Journal Papers > Research Organization > Institute for Medical Sciences
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