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Comparison of ablation efficacy of excimer, pulsed-dye, and holmium-YAG lasers relevant to shock waves.

DC Field Value Language
dc.contributor.authorTomaru, T-
dc.contributor.authorGeschwind, HJ-
dc.contributor.authorBoussignac, G-
dc.contributor.authorLange, F-
dc.contributor.authorTahk, SJ-
dc.date.accessioned2011-09-02T01:11:09Z-
dc.date.available2011-09-02T01:11:09Z-
dc.date.issued1992-
dc.identifier.issn0002-8703-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/3998-
dc.description.abstractAblation efficacy of pulsed lasers on human arterial tissue and associated shock waves have been investigated by means of excimer laser at 308 nm, pulsed-dye laser at 480 nm, and holmium-YAG laser at 2.1 microns. A multifiber catheter was used for lasing at 420 mjoules/pulse with holmium-YAG, 18.9 mjoules/pulse with excimer, and 100 mjoules/pulse with pulsed-dye laser. Ablation efficiency (ablated volume/energy) was greatest with pulsed-dye laser in blood and excimer laser in saline solution. There was selectivity for atheroma with pulsed-dye laser (ablation efficiency in atheroma versus normal tissue, 58 versus 27 x 10(-2) mm3/joule in blood; p less than 0.005) and holmium-YAG laser (12.6 versus 5.6 x 10(-2) mm3/joule in blood; p less than 0.001). Ablation efficiency of pulsed-dye laser was enhanced by blood (0.58 in blood versus 0.17 mm3/joules in saline for atheroma; p less than 0.005). Shock waves were correlated with ablation efficiency (r = 0.63 and 0.74 for pulsed-dye laser and holmium-YAG laser, respectively). There was neither selectivity for atheroma nor influence of blood medium with excimer laser. Only holmium-YAG laser could ablate tissue at a distance from the target in the blood medium. Histologic findings showed that all lasers could create smooth-edged craters with minimal coagulation necrosis. In conclusion, laser irradiation with holmium-YAG and pulsed-dye lasers could selectively ablate atheromatous tissue with minimal thermal injury, whereas excimer laser could not. Ablation efficiency was correlated with shock waves. Efficiency of pulsed-dye laser was enhanced by blood.-
dc.language.isoen-
dc.subject.MESHAngioplasty, Laser/adverse effects/*instrumentation/statistics & numerical data-
dc.subject.MESHAorta/pathology/surgery-
dc.subject.MESHArteriosclerosis/pathology/surgery-
dc.subject.MESHBlood-
dc.subject.MESHCatheterization, Peripheral/instrumentation-
dc.subject.MESHEvaluation Studies as Topic-
dc.subject.MESHHumans-
dc.subject.MESHSodium Chloride-
dc.subject.MESHUltrasonics/*adverse effects-
dc.titleComparison of ablation efficacy of excimer, pulsed-dye, and holmium-YAG lasers relevant to shock waves.-
dc.typeArticle-
dc.identifier.pmid1549996-
dc.contributor.affiliatedAuthor탁, 승제-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/0002-8703(92)90692-O-
dc.citation.titleAmerican heart journal-
dc.citation.volume123-
dc.citation.number4Pt1-
dc.citation.date1992-
dc.citation.startPage886-
dc.citation.endPage895-
dc.identifier.bibliographicCitationAmerican heart journal, 123(4Pt1):886-895, 1992-
dc.identifier.eissn1097-6744-
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Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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