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Gastric cancer in young patients who underwent curative resection. Comparative study with older patients.

Authors
Choi, JH; Chung, HC; Yoo, NC; Lee, HR; Lee, KH; Kim, JH; Roh, JK; Park, CS; Min, JS; Lee, KS; Kim, BS; Lim, HY
Citation
American journal of clinical oncology, 19(1):45-48, 1996
Journal Title
American journal of clinical oncology
ISSN
0277-37321537-453X
Abstract
Although several studies demonstrated the poor prognosis of young patients with gastric cancer, there were few reports about the survival of young patients who underwent radical surgery. We retrospectively reviewed the hospital records of 697 patients with curatively resected locally advanced gastric cancer to compare the pathologic findings and prognosis of young patients (aged or = 40 years; 606 patients) patients. There were no significant differences in location of tumors, Borrmann types, tumor invasion, and pathologic stage between both age groups. Despite the male predominance in older patients, the male-to-female ratio was nearly equal in young patients (p = 0.022). A significantly higher percentage of young patients showed poorly differentiated histology including signet ring cell and undifferentiated carcinoma than older patients (p < 0.0001). Adjuvant chemotherapy was more frequently performed in the young patients with a variety of different regimens (85.7 vs. 72.3%; p = 0.009). The 5-year overall survival rate revealed no statistically significant differences between the young and older patients (53.1 vs. 56.6%; p = 0.820). In conclusion, the young patients with curatively resected locally advanced gastric cancer showed similar survival compared to that of older patients.
MeSH terms
AdultAge DistributionAge FactorsAntineoplastic Combined Chemotherapy Protocols/therapeutic useChemotherapy, AdjuvantFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesSex DistributionStomach Neoplasms/drug therapy/mortality/pathology/*surgerySurvival Analysis
PMID
8554035
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Hematology-Oncology
AJOU Authors
최, 진혁임, 호영
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