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Bilateral primary renal non-Hodgkin's lymphoma presenting with acute renal failure: successful treatment with systemic chemotherapy.

Choi, JH; Choi, GB; Shim, KN; Sung, SH; Han, WS; Baek, SY
Acta haematologica, 97(4):231-235, 1997
Journal Title
Acta haematologica
Primary renal non-Hodgkin's lymphoma (NHL) with acute renal failure is a very rare condition, which frequently occurs in bilateral renal involvement. We report a 26-year-old male with primary bilateral renal NHL presenting with acute renal failure. A CT scan of the abdomen showed markedly enlarged kidneys with multinodularity and para-aortic lymphadenopathy. A percutaneous renal biopsy demonstrated 'follicular center lymphoma, diffuse, small cell'. Thirteen cycles of systemic chemotherapy with cyclophosphamide-doxorubicin-vincristine-prednisolone (CHOP) and ifosfamide-methotrexate-etoposide-bleomycin (IMVP-Bleo) regimens were administered, which resulted in normalization of renal function with improvement of renal lymphoma. Since there was no further change of renal lesions after initial partial remission, a follow-up renal biopsy was performed 10 months after diagnosis, and no residual lymphoma was found.
MeSH terms
Acute Kidney Injury/*etiologyAdultAntineoplastic Combined Chemotherapy Protocols/*therapeutic useBleomycin/administration & dosageCyclophosphamide/administration & dosageDoxorubicin/administration & dosageEtoposide/administration & dosageHumansIfosfamide/administration & dosageKidney Neoplasms/*complications/drug therapy/pathologyLymphoma, Follicular/*complications/drug therapyMaleMethotrexate/administration & dosageNeoplasms, Multiple Primary/*complications/drug therapy/pathologyPrednisone/administration & dosageRemission InductionVincristine/administration & dosage
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Hematology-Oncology
AJOU Authors
최, 진혁
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