Cited 0 times in Scipus Cited Count

Widely varying TNF-alpha levels in patients with myasthenia gravis.

DC Field Value Language
dc.contributor.authorLee, JS-
dc.contributor.authorJoo, IS-
dc.contributor.authorSeok, JI-
dc.date.accessioned2010-12-06T01:36:36Z-
dc.date.available2010-12-06T01:36:36Z-
dc.date.issued2009-
dc.identifier.issn1590-1874-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/412-
dc.description.abstractAnimal studies have indicated an important role of tumor necrosis factor-alpha (TNF-alpha) in the pathogenesis of myasthenia gravis (MG), and trials of monoclonal antibodies that block TNF-alpha have shown clinical improvement. However, before a TNF-alpha blocking agent is proposed for treatment of MG, whether serum TNF-alpha level correlates with the patient's condition should be confirmed. Therefore, we evaluated the relationship between the serum TNF-alpha level and clinical factors, including the quantitative MG score and the anti-acetylcholine receptor antibody level, in 33 MG patients. TNF-alpha levels ranged from 0.44 to 3.63 pg/mL and did not correlate with clinical factors. Overall, we found that serum TNF-alpha levels varied greatly among MG patients.-
dc.language.isoen-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAutoantibodies-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHImmunosuppressive Agents-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyasthenia Gravis-
dc.subject.MESHReceptors, Nicotinic-
dc.subject.MESHReference Values-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHTumor Necrosis Factor-alpha-
dc.titleWidely varying TNF-alpha levels in patients with myasthenia gravis.-
dc.typeArticle-
dc.identifier.pmid19214380-
dc.contributor.affiliatedAuthor이, 진수-
dc.contributor.affiliatedAuthor주, 인수-
dc.type.localJournal Papers-
dc.identifier.doi10.1007/s10072-009-0023-0-
dc.citation.titleNeurological sciences-
dc.citation.volume30-
dc.citation.number3-
dc.citation.date2009-
dc.citation.startPage259-
dc.citation.endPage262-
dc.identifier.bibliographicCitationNeurological sciences, 30(3). : 259-262, 2009-
dc.identifier.eissn1590-3478-
dc.relation.journalidJ015901874-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Neurology
Files in This Item:
There are no files associated with this item.

qrcode

해당 아이템을 이메일로 공유하기 원하시면 인증을 거치시기 바랍니다.

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse