The Effect of Barbiturate and Propofol on Blood-Brain Barrier Disruption Induced by Mannitol
Mannitol 투여에 의한 Blood-brain Barrier Disruption시에 Barbiturate와 Propofol의 비교
윤, 수환; 안, 영환; 안, 영민; 조, 기홍; 조, 경기
Ajou medical journal, 1(1):296-300, 1996
Ajou medical journal; 아주의학
We compared the anesthetic effects of barbiturate and propofol on mannitol-induced blood- brain-barrier disruption in four groups of each 6 rats. Group I was a barbiturate saline control, group 2 was propofol saline control, group 3 given propofol mannitol, and group 4 given barbiturate mannitol. There was no significant difference between group 1 and 2, or between group 3 and 4. These results suggest that barbiturate can be replaced with propofol for anesthesia in mannitol-induced blood-brain-barrier disruption.
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