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A Case of Seronegative Rheumatoid Arthritis with Idiopathic Hypereosinophilic Syndrome

Other Title
특발성 호산구 증가 증후군과 동반된 혈청 음성 류마티스 관절염 1예
Authors
최, 정현; 정, 재욱; 송, 현주; 송, 경은; 최, 정희; 서, 유진; 박, 해심; 서, 창희
Citation
The Journal of the Korean Rheumatism Association, 10(2):200-205, 2003
Journal Title
The Journal of the Korean Rheumatism Association; 대한류마티스학회지
ISSN
2093-940X2233-4718
Abstract
The idiopathic hypereosinophilic syndrome (HES) is a disorder marked by the sustained overproduction of eosinophils. The disease is characterized by damage of multiple organ including heart, nerve system, skin and lung due to eosinophilic infiltration and the diagnosis is one of exclusion. Rheumatologic manifestations of HES are infrequent. In about 10∼40% of rheumatoid arthritis (RA) patients, persistent eosinophilia is observed. That can be due to the RA itself and is often associated with active disease and extra-articular features. Sometimes, it is attributed to the drug therapy, especially gold and penicillamine. We would like to report a 37-year-old female patient with HES who developed seronegative RA 2 years later.
Keywords
Idiopathic hypereosinophilic syndromeSeronegative rheumatoid arthritis
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
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