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A Case of Improved Refractory Uveitis in Behçet’s Disease after Infliximab Therapy

Other Title
Infliximab 치료 후 호전된 난치성 포도막염을 동반한 베체트병 1예
Authors
최, 정우; 최, 용준; 예, 영민; 김, 상하; 남, 동호; 박, 해심; 이, 마빈; 유, 호민; 서, 창희
Citation
The Journal of the Korean Rheumatism Association, 12(4):320-323, 2005
Journal Title
The Journal of the Korean Rheumatism Association; 대한류마티스학회지
ISSN
2093-940X2233-4718
Abstract
Behçet's disease is a multisystemic, chronic relapsing inflammatory disease characterized by vasculitides, mucocutaneous lesions, thrombophlebitis, arthritis. Among them, the ocular involvement is usual (50∼70%) and the most serious morbidity is blindness (20∼25% of those of affected). Immunosuppressive treatment is currently the main therapy in chronic relapsing uveitis, but many patients experience recurrent sight-threatening uveitis. T lymphocytes play an important role in the pathogenesis of uveitis by releasing cytokines such as tumor necrosis factor (TNF) α. There are some reports that the anti-TNFα treatment is effective in refractory Behçet's uveitis, but it has not been reported in Korea. We report a case of refractory uveitis in Behçet's disease which is improved after anti-TNFα therapy.
Keywords
Behçet's diseaseUveitisTNFαAnti-TNFα treatment
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
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