Intraoperative Cytologic Examination of CNS Glioma

Abstract

The cytologic findings of 18 cases of CNS glioma were reviewed to evaluate the accuracy and the usefulness of intraoperative cytologic examination in central nervous system lesions. Crush preparations were prepared from little tissue fragments followed by hotatoxylin-eosin staining. The accuracy of the cytologic examination to detect tumors in this study was 94.4%(17/18) and differentiation of low and high grade glioma was possible in 16 out of 17 cases. The detailed cytologic features are described. The cytologic examination of intracranial tumor in crush preparation is a very useful procedure to have rapid and reliable diagnosis, and to provide valuable information for therapeutic management as well as for further histologic study.