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Clinical Implication of Prostaglandin E2 Content in Lumbar Disc Disease

DC Field Value Language
dc.contributor.author김, 형석-
dc.contributor.author조, 기홍-
dc.contributor.author김, 기용-
dc.contributor.author안, 영환-
dc.contributor.author안, 영민-
dc.contributor.author윤, 수한-
dc.contributor.author조, 경기-
dc.date.accessioned2011-12-13-
dc.date.available2011-12-13-
dc.date.issued2000-
dc.identifier.issn1225-8245-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/4819-
dc.description.abstractObjective:A prospective biochemical assay of prostaglandin E2 content in symptomatic lumbar disc materials was done in order to clarify the pathogenesis of lumbar radiculopathy.



Patients and Methods:Forty-eight disc specimens were purified by a standard solid-phase extraction procedure and analyzed by an enzymelinked immunosorbent assay for prostaglandin E2. Clinical and anatomic correlations were evaluated with analysis of variance and t-test.



Results:Acute herniated lumbar disc diseases tended to be associated with a higher prostaglandin E2 content than degenerative lumbar disc disease. Sequestered discs tended to be associated with a higher prostaglandin E2 content than extruded discs, which also showed higher prostaglandin E2 content than protruded ones. A sciatica and positive straight leg raising test appeared to be associated with a higher prostaglandin E2 content than a negative test.



Conclusion:This result suggests that the level of prostaglandin E2 would be correlated with clinical symptom and sign in the inflammatory process of lumbar disc herniation.
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dc.language.isoko-
dc.titleClinical Implication of Prostaglandin E2 Content in Lumbar Disc Disease-
dc.title.alternative추간판내 Prostaglandin E2 양의 임상적 의의-
dc.typeArticle-
dc.identifier.urlhttp://www.jkns.or.kr/htm/abstract.asp?no=0042000195&m=0-
dc.subject.keywordIntervertebral disc herniation-
dc.subject.keywordRadiculopathy-
dc.subject.keywordProstaglandin E2-
dc.type.localJournal Papers-
dc.citation.titleTaehan Sinkyŏng Oekwa Hakhoe chi-
dc.citation.titleJournal of Korean Neurosurgical Society-
dc.citation.title대한신경외과학회지-
dc.citation.volume29-
dc.citation.number10-
dc.citation.date2000-
dc.citation.startPage1340-
dc.citation.endPage1344-
dc.identifier.bibliographicCitationTaehan Sinkyŏng Oekwa Hakhoe chi, 29(10):1340-1344, 2000-
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Journal Papers > School of Medicine / Graduate School of Medicine > Neurosurgery
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