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A Case of Lymphomatoid Papulosis after Allogenic Bone Marrow Transplatation

Other Title
동종 골수이식 후 발생한 림프종모양구진증 1예
최, 재명; 이, 현우; 강, 석윤; 장, 준호; 박, 준성; 최, 진혁; 임, 호영; 김, 효철; 이, 은소
The Korean journal of hematology, 40(2):111-115, 2005
Journal Title
The Korean journal of hematology
A twenty-year-old man developed pruritic papules on his right forearm on the 25th day after an allogeneic bone marrow transplantation from an HLA-matched related donor. The skin lesion turned out to be lymphomatoid papulosis, both histologically and immunophenotypically, not a GVHD skin lesion. Lymphomatoid papulosis is a chronic lymphoproliferative disease of the skin, characterized by recurrent crusts of pruritic papules, which initially appearing on the upper trunk and both extremities. The lesions heal spontaneously within 2∼8 weeks, usually leaving slightly depressed oval scars. Histologically, the lesions show wedge-shaped dense dermal infiltrates of lymphoid cells, with numerous eosinophils, neutrophils and atypical lymphocytes. As much as 50% of the infiltrates show atypical lymphocytes, and the dermal vessels may show endothelial swelling, fibrin deposition and red blood cell extravasation. We are reporting a case of spontaneously healing CD56+ lymphomatoid papulosis, in the patient who received bone marrow transplantation, is reported.
GVHDLymphomatoid papulosisBone marrow transplantation
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Journal Papers > School of Medicine / Graduate School of Medicine > Hematology-Oncology
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