Maternal depression is known to have important negative effects on mother, child and mother-child relationship. To review current research evidence of association between maternal depression and their children's health and development, relevant studies were identified using Medline and Kiss(Korean studies Information Service System). The majority of research has reported that children of mother with depression are at risk for impaired physical functioning, growth and developmental delays, and behavioral problems compared to general population. From these studies, it is suggested that these kinds of studies are necessary in this country to examine the relation between maternal depression and children's health and development. Recommendations are included for future research and screening programs for maternal depression.