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Clinical Analysis of Hepatocellular Carcinoma in Childr

Other Title
소아 간세포암의 임상 분석
Authors
한, 상욱; 정, 성은; 이, 성철; 박, 귀원; 김, 우기
Citation
Taehan Oekwa Hakhoe, 49(6):1019-1024, 1995
Journal Title
Taehan Oekwa Hakhoe; 대한외과학회지
ISSN
1226-0053
Abstract
Our study on 13 children with hepatocellular carcinoma who were treated in Seoul National University Hospital spanning from january, 1986 to April, 1995 revealed following results.

Their average age at diagnosis was 11 years(range, 8 years to 15 years) and there was a slight predilection for males in a ratio of 2.3 to one. The most common chief complaint was abdominal mass(46%) and enlarged livers were palpated in all 13

patients.

Whereas liver function tests were normal, -fetoprotein levels were significantly high and proved to be a useful tumor marker in follow-up. Seven children underwent resection for cure and one child had incomplete resection. Five of these patients

are

still alive except one patient with lung metastasis, and the disease free interval was 12.8 months(range, 3 to 27 months). The lung metastasis was eradicatedby chemotherapy and then the hepatoma was resected curatively. Five tumors could only be

biopsied; all ofthese patients died within 7 months regardless of what treatment they received. The 2 year survival rate is 41% and mean length of survival is 12.8 months. Improved techniques in liver resection and chemotherapy can prolong the

survival

rate of hepatocellular cancer of childhood and can be undertaken even for unresectable lesions.
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Journal Papers > School of Medicine / Graduate School of Medicine > Surgery
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