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Lagnerhans' Cell Immunohistochemistry of Open Cavity Mastoidectomized Sking

Other Title
면역조직화학적 방법을 이용한 유양동 삭개술후 개방공동 피부의 랑게르한스세포의 관한 연구
박, 기현; 전, 영명; 정, 명현; 김, 창규
Taehan Ibi Inhukwa Hakhoe chi, 37(5):925-932, 1994
Journal Title
Taehan Ibi Inhukwa Hakhoe chi; Journal of the Korean Otolaryngological Society; 대한이비인후과학회지
Cavity problems which can develop after an open cavity mastoidectomy have received much attention in the field of otology, Recently, the incidence of chronic otitis media has decreased due to better economic and health conditions, and as a



of middle ear surgery have also relatively decreased in number. Therefore, otologists should now engage themselves more in searching for a treatment for these cavity problems. One of the cavity problems is that squamous debris accumulates in the


canal which occasionally causes some trouble. Lately, histologic examination of this newly formed skin in the open-mastoidectomized cavity(cavity skin) was reported using a light and electron microscopic investigation (Park et al, 1989). However,

further investigation about morphology of the cavity skin was needed to compare with that of cholesteatoma matrix. Thus, the aim of this study was to quantitate Langerhans' cells in the cavity skin using the immunohistochemical technique and to


them with those in the cholesteatoma matrix and postauricular skin.

@ES The results obtained were as follows :

@EN 1) The Langerhans' cells in the cavity skin increased significantly, compared with those in the cholesteatoma matrix(p<0.05) and postauricular skin (p<0.05).

2) The Langerhans' cells in the cavity and cholesteatoma matrix had more numerous and longer dendritic processes than those in the postauricular skin.

3) The more inflammation was in the subeithelial connective tissue, the more Langerhans' cell in the cavity skin increased in number.
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Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
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