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Animal Models of Helicobacter pyori Infections

Other Title
Helicobacter pylori 감염 실험 동물모델
Authors
김, 영배; 함, 기백; 이, 기명; 한, 상욱; 김, 명욱
Citation
The Korean journal of gastroenterology, 37(6):399-405, 2001
Journal Title
The Korean journal of gastroenterology; Taehan Sohwagi Hakhoe chi
ISSN
1598-99922233-6869
Abstract
The establishment of laboratory animal models persistently infected with Helicobacter pylori (H. pylori) has been difficult, but strongly required to document the causative role of H. pylori on ensuing gastritis, peptic ulcer disease and even

gastric

cancer. Although H. pylori are generally regarded as the most important etiologic agent of chronic active gastritis, peptic ulcer diseases, primary gastric marginal zone lymphoma, and gastric cancer, the detailed pathogenic mechanisms are not

resolved.

In an effort to develop an animal model that could show the same course of the infection that occurs in the human host, diverse kinds of animal model have been proposed. This review attempted to highlight salient features of H. pylori-infected

animal

models.
Keywords
Animal modelHelicobacter pylori
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Gastroenterology
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