Kawasaki disease (KD) is an acute vasculitis of undetermined etiology in infancy and early childhood. There is no diagnostic test to confirm this disease and its diagnosis is made on clinical backgrounds. Most patients diagnosed are under 4 years of age. Here, we report a case of KD in an adult presented with clinical features of fever, headache, and skin rash. A 26-year-old male was presented with fever and headache of four days' duration and skin rash of three days' duration. Nausea and vomiting developed and the patient was treated with antibiotics under the impression of aseptic meningitis and became afebrile two days later. Laboratory findings revealed thrombocytosis, atypical lymphocytes, and elevated liver enzymes. Kawasaki disease was diagnosed, and intravenous immunoglobulin and low-dose aspirin (200mg/d) was administered. Echocardiogram did not reveal any coronary artery changes and the skin lesions disappeared. The patient was discharged after near normalization of the liver enzymes and is now being followed at our clinic.