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Angioedema-like facial swelling as a first manifestation of systemic lupus erythematosus

Other Title
맥관부종양 안면부종을 주소로 한 전신성 루푸스 1례
권, 오영; 서, 창희; 정, 성택; 남, 동호; 박, 해심
Chʿŏnsik mit alrerugi, 18(1):90-95, 1998
Journal Title
Chʿŏnsik mit alrerugi; Journal of asthma, allergy and clinical immunology; Korean journal of asthma, allergy and clinical immunology; 천식 및 알레르기
Angioedma is a group of disorders with multifactorial etiology but a similar clinical

expresion, is characterized by swelling of subcutaneous or submucosal tissue. Systemic

lupus erythematosus(SLE) Is a chronic multi-systemtic disease characterized by

inflammation and tissue damage resulting from deposition of auto-antibodies and immune

complex. We experienced a case of angioedema which was the first manifestation of

SLE in 24-year old female patient. She had suffered from severe facial edema and

multiple lymphadenopathy for six months and she also had pleural effusion, positive

anti-nuclear and anti-DNA antibody test. Marked de crease of C3 and C4 levels was

noted with normal antigenic level, and activity of Cl esterase inhibitor. The angioedema

was not improved with anti-hitamine agents and instead disappeared with use of

corticosteroid and non-steroidal anti-inflammatory drugs. Complement levels nor-malized

after corticosteroid treatment. We report a case of SLE which initial manifestation was

angioedemafist manifestation of systemic lupus erythematosus
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Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
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