A Study of Clinical Caracteristics of Cryptococcal Meningitis in 38 Cases
크립토코크스 뇌막염의 임상양상에 관한 연구(38예의 진단 및 치료를 중심으로)
김, 정연; 이, 준홍; 석, 승한; 허, 균
Taehan Sin'gyŏngkwa Hakhoe chi : sin'gyŏnghak, 13(2):298-304, 1995
Taehan Sin'gyŏngkwa Hakhoe chi : sin'gyŏnghak; Journal of the Korean Neurological Association : neurology
A clinical analysis was carried out in 38 patients with cryptococcal meningitis who were admitted at Severance hospital from January 1983 to June 1993. Age of patients ranged from 3 to 72 years (mean 37.5). The number of patients with underlying
disease were 19(50%), which are equal to the number of patients without associated disease.
The major presenting symptoms were headache in 36 patinets(95%), fever in 26 patients (68%), nausea and vomiting in 20 patients(53%) in that order. The brain imaging findings were adnormal in21 patients(57%). The antifungal therapy was done;
amphotericin B only in 3 patients; amphotericin B and flucytocine in 23 patients; fluconazole only in 5 patients. The therapeutic responses were good in 19 patients(50%). The patients with favorable outcome were younger less having focal deficit, seizure, or associated disease.
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