A Case of Acute Colchicine-induced Myopathy with Myotonia in Behcet Disease
베체트병에서 관찰된 콜치신에 의한 근긴장성 근병증 1예
오, 세호; 주, 인수; 주, 성렬; 이, 은소; 심, 철; 김, 장희
Taehan Sin'gyŏngkwa Hakhoe chi : sin'gyŏnghak, 21(1):220-223, 2003
Taehan Sin'gyŏngkwa Hakhoe chi : sin'gyŏnghak; Journal of the Korean Neurological Association : neurology
Colchicine has been used in the treatment of autoimmune diseases such as Behcet disease. Long-term use of colchicine can cause vacuolar myopathy on rare occasions. We report colchicine-induced myopathy with myotonia in Behcet disease. A 34-year-old man with Behcet disease presented progressive proximal weakness, myalgia, and difficulty in relaxation of grip after increasing the dosage of colchicine. Electrophysiological findings showed myotonic myopathy. Muscle biopsy revealed vacuolar myopathy. His symptoms were resolved with the discontinuation of colchicine.
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