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Topical Photodynamic Therapy for Treatment of Actinic Keratosis Using Light-Emitting Diode (LED) Device

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dc.contributor.author이, 중선-
dc.contributor.author김, 윤전-
dc.contributor.author강, 희영-
dc.contributor.author이, 은소-
dc.contributor.author오, 충훈-
dc.contributor.author김, 유찬-
dc.date.accessioned2012-03-08T05:34:08Z-
dc.date.available2012-03-08T05:34:08Z-
dc.date.issued2005-
dc.identifier.issn0494-4739-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/6040-
dc.description.abstractBackground: Photodynamic therapy is a treatment modality which involves the sequential administration of a photosensitizer and light. Topical photodynamic therapy is being increasingly used for superficial non-melanoma skin cancers and their precursors.
Objective: The purpose of this study was to evaluate the effectiveness and side effects of treating actinic keratosis with photodynamic therapy using a light-emitting diode device and 20% 5-aminolevulinic acid.
Methods: Photodynamic therapy, with a 630+/-50nm light-emitting diode device and 5-aminolevulinic acid, was used to treat 12 lesions of actinic keratosis on 8 patients. The light intensity used was 50mW/cm2 , and the light dose was 100-120J/cm2 . Four weeks after 1 or 2 treatment sessions, the outcome was evaluated by histopathological findings.
Results: Complete clearance was achieved in 8 of 12 lesions after a single treatment, and in 3 of 12 lesions after 2 treatment sessions. Only 1 case showed partial response after 2 treatment sessions. Only 2 patients suffered from a stinging sensation when exposed to the light therapy.
Conclusion: Topical photodynamic therapy using a light-emitting diode is safe and effective in the treatment of actinic keratosis.
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dc.formatapplication/pdf-
dc.language.isoko-
dc.titleTopical Photodynamic Therapy for Treatment of Actinic Keratosis Using Light-Emitting Diode (LED) Device-
dc.title.alternative광선각화증에서 Light-Emitting Diode (LED)를 이용한 국소 광역동요법의 치료효과-
dc.typeArticle-
dc.subject.keywordPhotodynamic therapy-
dc.subject.keywordLight-emitting diode-
dc.subject.keywordActinic keratosis-
dc.contributor.affiliatedAuthor이, 중선-
dc.contributor.affiliatedAuthor강, 희영-
dc.contributor.affiliatedAuthor이, 은소-
dc.contributor.affiliatedAuthor김, 유찬-
dc.type.localJournal Papers-
dc.citation.titleKorean journal of dermatology-
dc.citation.volume43-
dc.citation.number4-
dc.citation.date2005-
dc.citation.startPage469-
dc.citation.endPage474-
dc.identifier.bibliographicCitationKorean journal of dermatology, 43(4). : 469-474, 2005-
dc.relation.journalidJ004944739-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Dermatology
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