A Case of Palisaded Encapsulated Neuroma of the Eyelid
상안검에 발생한 Palisaded Encapsulated Neuroma 1예
천, 은영; 조, 영훈; 김, 유찬; 방, 동식
Korean journal of dermatology, 42(12):1603-1605, 2004
Korean journal of dermatology; 대한피부과학회지
Palisaded encapsulated neuroma (PEN) is a rare intraneural neuroma. It usually occurs as a solitary asymptomatic skin-colored papule, and commonly affects the butterfly area of the face of middle-aged adults. We report a case of PEN which developed on the right upper eyelid of a 30-year-old man. It was a 3 mm-sized skin colored papule, and histologically, there was a well- defined encapsulated nodule in the dermis, composed of spindle cells with basophilic and plump nuclei in a palisading pattern. On immunohistochemical staining, the tumor cells of the nodule were positive for S-100 protein, while the capsule of the nodule was positive for epithelial membrane antigen.
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