Acute Generalized Exanthematous Pustulosis(AGEP) Induced by Ampicillin
Ampicillin 복용후 발생한 급성 전신성 발진형 농포증 2예
전, 세정; 김, 남수; 이, 은소; 강, 원형
Korean journal of dermatology, 36(2):355-359, 1998
Korean journal of dermatology; 대한피부과학회지
We report cases of two patients with acute generalized exanthematous
pustulosis(AGEP). One patient had localized cutaneous infection and the other
rhinoplasty. Both were being treated with ampicillin and developed intense erythemas
followed by generalized subcomeal pustulation associated with fever and a neutrophilic leukocytosis. Histopathological findings were subcorneal spongiform pustules showing preponderance of polylnorphonuclear leukocytes. Generalized pustular psoriasis, subcorneal pustular dermatosis, impetigo and pemphigus foliaceus should be differentiated from AGEP The causative drug in both of our cases was ampicillin and fast resolution of
pustules was observed with a low dosage of systemic steroid within 5 days.
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