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Long-term safety and effectiveness of unprotected left main coronary stenting with drug-eluting stents compared with bare-metal stents.
DC Field | Value | Language |
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dc.contributor.author | Kim, YH | - |
dc.contributor.author | Park, DW | - |
dc.contributor.author | Lee, SW | - |
dc.contributor.author | Yun, SC | - |
dc.contributor.author | Lee, CW | - |
dc.contributor.author | Hong, MK | - |
dc.contributor.author | Park, SW | - |
dc.contributor.author | Seung, KB | - |
dc.contributor.author | Gwon, HC | - |
dc.contributor.author | Jeong, MH | - |
dc.contributor.author | Jang, Y | - |
dc.contributor.author | Kim, HS | - |
dc.contributor.author | Seong, IW | - |
dc.contributor.author | Park, HS | - |
dc.contributor.author | Ahn, T | - |
dc.contributor.author | Chae, IH | - |
dc.contributor.author | Tahk, SJ | - |
dc.contributor.author | Chung, WS | - |
dc.contributor.author | Park, SJ | - |
dc.contributor.author | Revascularization for Unprotected Left Main Coronary Artery Stenosis: Comparison of Percutaneous Coronary Angioplasty Versus Surgical Revascularization Investigators | - |
dc.date.accessioned | 2010-12-16T06:59:00Z | - |
dc.date.available | 2010-12-16T06:59:00Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0009-7322 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/630 | - |
dc.description.abstract | BACKGROUND: Limited information is available on long-term outcomes for patients with unprotected left main coronary artery disease who received drug-eluting stents (DES).
METHODS AND RESULTS: In the multicenter registry evaluating outcomes among patients with unprotected left main coronary artery stenosis undergoing stenting with either bare metal stents (BMS) or DES, 1217 consecutive patients were divided into 2 groups: 353 who received only BMS and 864 who received at least 1 DES. The 3-year outcomes were compared by use of the adjustment of inverse-probability-of-treatment-weighted method. Patients receiving DES were older and had a higher prevalence of diabetes mellitus, hypertension, hyperlipidemia, and multivessel disease. In the overall population, with the use of DES, the 3-year adjusted risk of death (8.0% versus 9.5%; hazard ratio, 0.71; 95% confidence interval, 0.36 to 1.40; P=0.976) or death or myocardial infarction (14.3% versus 14.9%; hazard ratio, 0.83; 95% confidence interval, 0.49 to 1.40; P=0.479) was similar compared with BMS. However, the risk of target lesion revascularization was significantly lower with the use of DES than BMS (5.4% versus 12.1%; hazard ratio, 0.40; 95% confidence interval, 0.22 to 0.73; P=0.003). When patients were classified according to lesion location, DES was still associated with lower risk of target lesion revascularization in patients with bifurcation (6.9% versus 16.3%; hazard ratio, 0.38; 95% confidence interval, 0.18 to 0.78; P=0.009) or nonbifurcation (3.4% versus 10.3%; hazard ratio, 0.39; 95% confidence interval, 0.17 to 0.88; P=0.024) lesions with a comparable risk of death or myocardial infarction. CONCLUSIONS: Compared with BMS, DES was associated with a reduction in the need for repeat revascularization without increasing the risk of death or myocardial infarction for patients with unprotected left main coronary artery stenosis. | - |
dc.language.iso | en | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary | - |
dc.subject.MESH | Coronary Restenosis | - |
dc.subject.MESH | Coronary Stenosis | - |
dc.subject.MESH | Diabetic Angiopathies | - |
dc.subject.MESH | Drug-Eluting Stents | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hyperlipidemias | - |
dc.subject.MESH | Hypertension | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Metals | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Infarction | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Registries | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Safety | - |
dc.title | Long-term safety and effectiveness of unprotected left main coronary stenting with drug-eluting stents compared with bare-metal stents. | - |
dc.type | Article | - |
dc.identifier.pmid | 19620506 | - |
dc.identifier.url | http://circ.ahajournals.org/cgi/pmidlookup?view=long&pmid=19620506 | - |
dc.contributor.affiliatedAuthor | 탁, 승제 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1161/CIRCULATIONAHA.108.800805 | - |
dc.citation.title | Circulation | - |
dc.citation.volume | 120 | - |
dc.citation.number | 5 | - |
dc.citation.date | 2009 | - |
dc.citation.startPage | 400 | - |
dc.citation.endPage | 407 | - |
dc.identifier.bibliographicCitation | Circulation, 120(5). : 400-407, 2009 | - |
dc.identifier.eissn | 1524-4539 | - |
dc.relation.journalid | J000097322 | - |
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