Correlation of Infarct Size and Late Troponin T Peak Concentration in Acute Myocardial Infarction
급성심근경색에서 Troponin T와 경색의 크기와의 상관관계
서, 창희; 김, 한수; 강, 한걸; 신, 준한; 탁, 승제; 이, 승호; 최, 병일
The Korean journal of medicine, 52(1):66-74, 1997
The Korean journal of medicine; 대한내과학회지
@EN The estimation of infarct size has been important in evaluation of prognosis of the patients who had acute myocardial infarction. The infarct size estimated by the thallium-201 SPECT has been known to correlate with the prognosis of patients.
The enzymatic estimation by the total release of creatine kinase isoenzyme MB(CK-MB) has been widely used in estimating infarct size clinically, but inconvienent and not cardiospecific. Recently, serum troponin T, cardiospecific myofibrillar protein, has been used in the diagnosis of acute myocardial infarction, and used in the estimation of reperfusion following myocardial infarction.
@EN The patients with acute myocardial infarction who were admitted, within 48 hours after the onset of chest pain, to Ajou University Hospital between April 1995 and August 1995 were evaluated. All patients were divided into anterior and inferior
infarct and checked serum troponin T and CK-MB serially, and underwent stress Thallium-201 SPECT 1 week after infarction. In each group, we assessed the correlation of the late toponin T peak concentration, the total release of CK-MB, and the infarct size estimated by thallium-201 single photon emission computed tomography(SPECT).
@EN 1) The eligible subjects consisted of 22 patients (17 men and 5 women), and age ranged from 29 to 77 years(mean 57.8±12.5 years).
@EN The late troponin T peak concentration was more accurate than the total release of CK-MB in the estimation of infarct size.
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