Climactic changes are key environmental issues affecting allergic diseases. Temperature and CO2 content have been found to be increasing together with climate changes, which could increase pollen production, extend the pollination period, and augment the allergenic components of major pollens. Changes in the distribution of major trees and weeds have been noted. Severe weather events such as thunderstorm winds and precipitation could increasingly cause pollen grains to burst, releasing allergenic particles and leading to extensive mold growth. Air pollutants can increase the concentration of allergen released from pollen grains and allow for easier penetration into airway mucosa. Future studies will be essential to investigate the mechanisms by which allergenic contents can be changed in response to climate change. A better understanding of how aeroallergens interact with air pollutants is needed. Climate change has a significant impact on aeroallergen levels and content in ways which may accelerate the development of allergic diseases. Future strategies will be crucial in preventing the allergic diseases associated with climate changes.