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Women with fibromyalgia have lower levels of calcium, magnesium, iron and manganese in hair mineral analysis.

Authors
Kim, YS; Kim, KM; Lee, DJ; Kim, BT; Park, SB; Cho, DY; Suh, CH; Kim, HA; Park, RW; Joo, NS
Citation
Journal of Korean medical science, 26(10):1253-1257, 2011
Journal Title
Journal of Korean medical science
ISSN
1011-89341598-6357
Abstract
Little is known about hair mineral status in fibromyalgia patients. This study evaluated the characteristics of hair minerals in female patients with fibromyalgia compared with a healthy reference group. Forty-four female patients diagnosed with fibromyalgia according to the American College of Rheumatology criteria were enrolled as the case group. Age and body mass index-matched data were obtained from 122 control subjects enrolled during visit for a regular health check-up. Hair minerals were analyzed and compared between the two groups. The mean age was 43.7 yr. General characteristics were not different between the two groups. Fibromyalgia patients showed a significantly lower level of calcium (775 µg/g vs 1,093 µg/g), magnesium (52 µg/g vs 72 µg/g), iron (5.9 µg/g vs 7.1 µg/g), copper (28.3 µg/g vs 40.2 µg/g) and manganese (140 ng/g vs 190 ng/g). Calcium, magnesium, iron, and manganese were loaded in the same factor using factor analysis; the mean of this factor was significantly lower in fibromyalgia group in multivariate analysis with adjustment for potential confounders. In conclusion, the concentrations of calcium, magnesium, iron, and manganese in the hair of female patients with fibromyalgia are lower than of controls, even after adjustment of potential confounders.
MeSH terms
AdultBody HeightBody Mass IndexCalcium/analysisFemaleFibromyalgia/*metabolismHair/*chemistryHumansIron/analysisMagnesium/analysisManganese/analysisMetals/*analysisMiddle Aged
DOI
10.3346/jkms.2011.26.10.1253
PMID
22022174
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Family Practice & Community Health
Journal Papers > School of Medicine / Graduate School of Medicine > Rheumatology
Journal Papers > School of Medicine / Graduate School of Medicine > Medical Informatics
AJOU Authors
김, 영상김, 광민이, 득주김, 범택박, 샛별조, 두연서, 창희김, 현아박, 래웅주, 남석
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